
Bradykinin (1-6)
CAS No. 23815-88-5
Bradykinin (1-6)( —— )
Catalog No. M30445 CAS No. 23815-88-5
Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).Bradykinin (1-6) is a fragment of bradykinin. Bradykinin activates pain receptors. It induces smooth muscle contractions and activates Ca2+-dependent nitric oxide synthetase.
Purity : >98% (HPLC)






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Biological Information
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Product NameBradykinin (1-6)
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NoteResearch use only, not for human use.
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Brief DescriptionBradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).Bradykinin (1-6) is a fragment of bradykinin. Bradykinin activates pain receptors. It induces smooth muscle contractions and activates Ca2+-dependent nitric oxide synthetase.
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DescriptionBradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).Bradykinin (1-6) is a fragment of bradykinin. Bradykinin activates pain receptors. It induces smooth muscle contractions and activates Ca2+-dependent nitric oxide synthetase. (In Vivo):Bradykinin (1-6) is a stable metabolite of Bradykinin in rat urine. Bradykinin (BK) is very active in renal function because it participates in increasing the renal blood flow and in diuresis and natriuresis.
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In Vitro——
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In VivoBradykinin (1-6) is a stable metabolite of Bradykinin in rat urine. Bradykinin (BK) is very active in renal function because.it participates in increasing the renal blood flow and in diuresis and natriuresis.
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Synonyms——
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PathwayGPCR/G Protein
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TargetBradykinin Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number23815-88-5
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Formula Weight659.73
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Molecular FormulaC30H45N9O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (151.58 mM)
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SMILES——
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Chemical NameSequence:Arg-Pro-Pro-Gly-Phe-Ser
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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Bradykinin (1-6)
Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).Bradykinin (1-6) is a fragment of bradykinin. Bradykinin activates pain receptors. It induces smooth muscle contractions and activates Ca2+-dependent nitric oxide synthetase.
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MEN 11270
Peptide antagonist of the B2 bradykinin receptor (pKi = 10.3); conformationally constrained cyclized analog of HOE 140. Blocks hypotension and bronchoconstriction in vivo. Displays selectivity for B2 over 29 other receptors and ion channels (pIC50 < 5.5).
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Bradykinin (acetate)
Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions. Enzymatically produced from kallidin in the blood, it is a powerful vasodilator that causes smooth muscle contraction, and may mediate inflammation.